Statistical and Chemometric Tools Applied to Pharmaceutical Analysis

Applied Multivariate Statistical Analysis

Thermal analysis applied to verapamil hydrochloride characterization in pharmaceutical formulations.

Thermogravimetry (TG) and differential scanning calorimetry (DSC) are useful techniques that have been successfully applied in the pharmaceutical industry to reveal important information regarding the physicochemical properties of drug and excipient molecules such as polymorphism, stability, purity, formulation compatibility among others. Verapamil hydrochloride shows thermal stability up to 18...

Parsing Tools Applied to ELANM

Optimization of wavelength range and data interval in chemometric analysis of complex pharmaceutical mixtures☆

The performance of different chemometric approaches was evaluated in the spectrophotometric determination of pharmaceutical mixtures characterized by having the amount of components with a very high ratio. Principal component regression (PCR), partial least squares with one dependent variable (PLS1) or multi-dependent variables (PLS2), and multivariate curve resolution (MCR) were applied to the...

Statistical analysis of immigrants to Abyssinia

immigration to Abyssinia, which took place at the beginning of the official invitation of the Prophet (PBUH) in the fifth year of the Besat, is of the most important events in the history of Islam. There are few historical documents of this immigration. Lack of information has prevented proper historical research about this immigration. Hence, the causes, manner and consequences of immigrating ...